منابع مشابه
Improvement of impaired diastolic left ventricular function after diet-induced weight reduction in severe obesity
BACKGROUND/OBJECTIVES Obesity is independently associated with left ventricular (LV) diastolic dysfunction and altered cardiac morphology. Morbidity and mortality in patients with diastolic dysfunction are similar to values observed in patients with systolic heart failure. We hypothesized that dysfunctional cardiac responses in people with obesity are reversible after weight loss. Thus, we stud...
متن کاملImpaired left ventricular function in obesity?
We read with interest the findings of Sasso et al. regarding the effects of insulin on left ventricular function during exercise in obese subjects. The authors conclude that their results ‘suggest a metabolic pathogenesis for the impaired left ventricular function in obesity’. This may be true, but the data they divulge do not support this conclusion. Most importantly, their interpretation that...
متن کاملDiastolic function of the right ventricle is impaired in experimental type 2 diabetic rat models.
AIM To evaluate diastolic function alterations of the right ventricle (RV) by echocardiography in type 2 diabetic rat models. MATERIALS AND METHODS Male Wistar rats were divided into 2 groups: a control group (n = 8) and a diabetic group (n = 16, with 11 remaining at the end of the experiment), which was fed a high-fat and high-calorie diet and injected with streptozotocin (STZ). RV diastolic...
متن کاملDiastolic function is strongly and independently associated with cardiorespiratory fitness in central obesity.
Cardiorespiratory fitness [maximal O2 consumption (VO2max)] is an independent risk factor for type 2 diabetes; but in individuals at risk, factors influencing VO2max are poorly understood. We tested the hypothesis that VO2max is associated with diastolic function [subendocardial variability ratio (SEVR), %], as diastolic function influences myocardial perfusion. We studied 47 men and women with...
متن کاملUncomplicated obesity is associated with abnormal aortic function assessed by cardiovascular magnetic resonance
AIMS Obese subjects with insulin resistance and hypertension have abnormal aortic elastic function, which may predispose them to the development of left ventricular dysfunction. We hypothesised that obesity, uncomplicated by other cardiovascular risk factors, is independently associated with aortic function. METHODS AND RESULTS We used magnetic resonance imaging to measure aortic compliance, ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1995
ISSN: 0735-1097
DOI: 10.1016/0735-1097(95)92850-5